S-Adenosyl-L-Methionine is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.

SAMe contains S-Adenosyl-L-Methionine, an essential amino acid required for optimal cellular functioning. S Adenosyl L Methionine is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and enhances liver metabolism. S Adenosyl L Methionine increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.